Cytotoxic and antiproliferative effects of hellebrin on breast and lung cancer cells

This study aimed to investigate the impact of hellebrin on human lung cancer cell (H1299) and breast (MCF-7) lines over time. The viability various concentrations (100 nM-400 nM) two was measured using MTT method. cellular proliferation time examined xCELLigence real-time analysis (RTCA). results showed a significant decrease in with increasing both compared control group (p˂0.0001). While cells decreased after certain period application, groups increased These findings indicate that has high antiproliferative cytotoxic effects cells. Consequently, this suggests may have potential as treatment for other cancers, especially cancer, further vitro vivo experiments are needed possibility.